 DNA and RNA Binders , 2 Volume Set, From Small Molecules to Drugs
ISBN: 978-3-527-30595-7
Hardcover
754 pages
February 2003
US $515.00
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Preface.
Contributors.
1. Forty Years On (Michael J. Waring and L. P. G. Wakelin).
2. Targeting HIV RNA with Small Molecules (Nathan W. Luedtke and Yitzhak Tor).
3. RNA Targeting by Bleomycin (Sidney M. Hecht).
4. Inhibitors of the Tat-TAR Interactions (Chimmanamada U. Dinesh and Tariq M. Rana).
5. DNA and RNA Recognition and Modification by Gly-Gly-His-Derived Metallopeptides (Eric C. Long and Craig A. Claussen).
6. Salen-Metal Complexes (S. E. Rokita and C. J. Burrows).
7. Charge Transport in DNA (Tashica T. Williams and Jacqueline K. Barton).
8. DNA Interactions of Novel Platinum Anticancer Drugs (Viktor Brabec and Jana Kasparkova).
9. Electrochemical Detection of DNA with Small Molecules (Shigeori Takenaka).
10. Design and Studies of Abasic Site Targeting Drugs: New Strategies for Cancer Chemotherapy (Jean-Francois Constant and Martine Demeunynck).
11. Interactions of Macrocyclic Compounds with Nucleic Acids (Marie-Paule Teulade-Fichou and Jean-Pierre Vigneron).
12. Triplex- versus Quadruplex-specific Ligands and Telomerase Inhibition ( Patrizia Alberti, et al.)
VOLUME 2.
13. Design and Analysis of G4 Recognition Compounds (Shozeb Haider, et al.).
14. Triple Helix-specific Ligands (Keith R. Fox and Richard A. J. Dardy).
15. Polyamide Dimer Stacking in the DNA Minor Groove and Recognition of T·G Mismatched Base Pairs in DNA (Eilyn R. Lacy, et al.).
16. Dicationic DNA Minor Groove Binders as Antimicrobial Agents (Richard R. Tidwell and David W. Boykin).
17. Energetics of Anthracycline-DNA Interactions (Jonathan B. Chaires).
18. Acridine-4-carboxamides and the Concept of Minimal DNA Intercalators (William A. Denny).
19. DNA Topoisomerase-targeted Drugs (M. Palumbo, et al.).
20. Targeting DNA and Topoisomerase 1 with Indolocarbazole Antitumor Agents (Christian Bailly).
21. Defining the Molecular Interactions that are Important for the Poisoning of Human Topoisomerase 1 by Benzimidazoles and Terbenzimidazoles (Daniel S. Pilch, et al.).
22. Binding and Reaction of Calicheamicin and Other Enediyne Antibiotics with DNA (Joseph P. Cosgrove and Peter C. Dedon).
23. Devising a Structural Basis for the Potent Cytotoxic Effects of Ecteinascidin 743 (Federico Gago and Laurence H. Hurley).
24. The Azinomycins Discovery, Synthesis, and DNA-binding Studies (Maxwell Casely-Hayford and Mark Searcey).
25. The Generation and DNA-Interaction of PBD and CBI Libraries (Alison Hardy, et al.).
Index.
